Mantoux TB Skin Test Unsafe and Unreliable



The TB skin test, also known as the Mantoux test, tells if your body has been exposed to the TB germ.
The nurse will inject a small amount of fluid just under the skin of the left forearm.
You will see a little bubble or blister appear right away at the injection site. This is normal and it will soon disappear.

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After 2-3 days, you will be asked to see the nurse to have the area checked and the reaction measured.
If there is no reaction after 2-3 days, you most probably have not been exposed to the TB germ.
If there is a reaction, some redness and a small bump will appear on the arm.
A measurement of 10 millimetres or more is “positive”, and means you may have the TB germ in your body.


At that point, the nurse will request additional information and tests, including chest x-ray and the collection of sputum samples. When results are abnormal, the nurse will then consult with a medical health officer who may then recommend a further course of action.


For a more detailed description, click HERE


Aplisol Tuberculin contains harmful ingredients such as polysorbate 80 and phenol.

Another brand called Tubersol contains Phenol but it seems no polysorbate 80 HERE

The Mantoux test is not only harmful, but also unreliable as this paper shows:

Unreliability of the Mantoux test using 1 TU PPD in excluding childhood tuberculosis in Papua New Guinea HERE

Also read ‘Dr Len Horowitz on TB Test’ HERE


Tuberculin is the fluid injected for the Mantoux Test.

Here is the Material Safety Data Sheet for a Aplisol which appears to be a commonly used brand of Tuberculin:


Aplisol® Tuberculin Material Safety Data Sheet
(Tuberculin Purified Protein Derivative, Diluted [Stabilized Solution])

Product Summary
Therapeutic Area: Hospital Products
This product is distributed by: JHP Pharmaceuticals, LLC

Full Prescribing Information (NEW PI)

MSDS Sheet


For additional product information please see our contact page.

Product Strength Vial Size Unit of Sales Current NDC Previous NDC
Aplisol® (Tuberculin Purified Protein Derivative, diluted) 5TU/0.1mL 1 mL MDV 1 42023-104-01 64029-4525-1
Aplisol® (Tuberculin Purified Protein Derivative, diluted) 5TU/0.1mL 5 mL MDV 1 42023-104-05 64029-4525-2

• Equivalent to the 5 TU dose recommended as clinically established and standardized with PPD-S
• The result is read 48 to 72 hours later by a healthcare professional and induration only is considered in interpreting the test.

Aplisol (tuberculin PPD, diluted) is a sterile aqueous solution of a purified protein fraction for intradermal administration as an aid in the diagnosis of tuberculosis. The solution is stabilized with polysorbate (Tween) 80, buffered with potassium and sodium phosphates and contains approximately 0.35% phenol as a pre-servative. This product is ready for immediate use without further dilution.

Tuberculin PPD is recommended by the American Lung Association as an aid in the detection of infection with Mycobacterium tuberculosis. The standard tuberculin test recommended employs the intradermal (Mantoux) test using a 5 TU dose of tuberculin PPD.7 The 0.1-mL test dose of Aplisol (tuberculin PPD, diluted) is equivalent to the 5 TU dose recommended as clinically established and standardized with PPD-S. Tuberculin skin testing is not contraindicated for persons who have been vaccinated with BCG and the skin-test results of such persons are used to support or exclude the diagnosis of M. tuberculosis infections.4 HIV infection is a strong risk factor for the development of TB disease in persons having TB infection. All HIV-infected persons should receive a PPD-tuberculin skin test.3

Aplisol is contraindicated in patients with known hypersensitivity or allergy to Aplisol or any of its com-ponents. Aplisol should not be administered to persons who have previously experienced a severe reaction (e.g., vesiculation, ulceration, or necrosis) because of the severity of reactions that may occur at the test site.

Not all infected persons will have a delayed hypersensitivity reaction to a tuberculin test. A number of factors have been reported to cause a decreased ability to respond to the tuberculin test, such as the presence of infections, viral infections (measles, mumps, chickenpox, HIV), live virus vaccinations (measles, mumps, rubella, oral polio, varicella and yellow fever), bacterial infections (typhoid fever, brucellosis, typhus, leprosy, pertussis, overwhelming tuberculosis, tuberculous pleurisy), fungal infections (South American blastomycosis), drugs (corticosteroids and other immunosuppressive agents), metabolic derangements (chronic renal failure), low protein states (severe protein depletion, afibrinogenemia), age (newborns, elderly patients with waned sensitivity), stress (surgery, burns, mental illness, graft-versus-host reactions), diseases affecting lymphoid organs (Hodgkin’s disease, lymphoma, chronic leukemia, sarcoidosis), and malignancy.7,8,9

Any condition that impairs or attenuates cell mediated immunity potentially can cause a false negative reaction, including aging. 10,11

Tuberculin skin test results are less reliable in HIV-infected individuals as CD4 counts decline (see CLINICAL

Avoid injecting tuberculin subcutaneously. If this occurs, no local reaction develops, but a general febrile reaction and/or acute inflammation around old tuberculous lesions may occur in highly sensitive individuals.

In highly sensitive individuals, strongly positive reactions including vesiculation, ulceration or necrosis may occur at the test site; however, there were no reports of these reactions for the period 1995 through 1998. Cold packs or topical steroid preparations may be employed for symptomatic relief of the associated pain, pruritus and discomfort. Strongly positive test reactions may result in scarring at the test site. Immediate erythematous or other reactions may occur at the injection site.

Please see the full prescribing information link above for additional information and references.


CaptureAlternative TB Test


Slide source

– Mantoux test reactions

Posted on the Vaccination Information Network Facebook page on 4 September 2015

Traci Leadstrom I had a horrible reaction to a TB skin test. Immune disfunction, sore and swollen joints, adrenal crash. My doctor said many people are reacting to the preservative in it. I would steer clear of the injection. Most states will allow a X-ray and doctors note.

Diedra Giles I get physically ill (vomiting/diarrhea) for 3 – 4 days after getting it. I refuse now.


Watch the cruelty of vaccines first hand, as this young Thai girl is brutalised by the medical establishment